conjugation DAR

0 0 hace 10 meses
ADC antibody occasionally induces antigen-mediated anticancer activity. Other challenges for targeting tumor antigens with ADCs include high stromal tumor pressure, physiological and kinetic energy barriers, and bystander effects.
Second-generation ADC is more stable than the first-generation connector, the toxic load is more effective, but based on the random coupling strategy, the conjugation DAR is heterogeneous, the drug stability is low, the non-specific toxicity is increased, and the ... Más informaciones

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